Vaccine Case Studies

MVI Portfolio Management Process (Public-Private Partnership)

Situation

The Malaria Vaccine Initiative (MVI) is a public-private partnership formed in 1999 to accelerate the development of promising malaria vaccine candidates and ensure their availability and accessibility in the developing world. MVI faced challenges in how to leverage key learning from historic and ongoing malaria vaccine projects to shape a long-term R&D strategy for its portfolio of vaccine candidates. This was important in building a case for its Core Grant Renewal.

Applied Strategies worked with MVI to develop a five-year R&D strategy for proactively and successfully managing a portfolio in a highly uncertain development environment.

Contribution

• Portfolio approach to R&D
• Transparent and consistent portfolio characterization
• Clinical Trial outcome identification and follow-on activity planning
• Go/no-go investment decision criteria
• Ensuring Execution
  • Comprehensive strategy implementation plan to ensure a successful rollout, completion of key design activities, and ongoing system monitoring and refinement
  • Facilitate effective and credible reviews with key stakeholders (donors,suppliers and countries)

Results

• Laid the foundation for MVI to create its Core Grant Renewal proposal
• Defined the metrics for and tracking accountability for their R&D strategy
• Designed and implemented a more effective project and portfolio management system
• Developed transparent and robust decision-making processes

<< back