Global Health Case Studies
Portfolio Management Systems in the Global Sector
The pharmaceutical industry has developed best practice portfolio
management processes that help maximize the potential value of the
company's R&D portfolio. In the global health community, portfolio
management is not routinely practiced, even though maximizing the
return on these investments is measured in lives saved.
The Malaria Vaccine Initiative (MVI) was founded in 1999 with a
mission to accelerate the development of promising malaria vaccine
candidates, and ensure their availability and accessibility in the
developing world. MVI has partnered with many academic, government,
and industry research and development organizations to support dozens
of vaccine trials, including several endemic population trials in Africa.
MVI's R&D portfolio currently contains 11 ongoing vaccine candidate
programs, including the first malaria vaccine to move into Phase III trials.
To ensure effective stewardship of its R&D portfolio on an ongoing
basis, MVI initiated a project with Applied Strategies to design and
implement a comprehensive portfolio management system. The scope of
this work included:
-
Establishing both internal and external advisory councils, management
committees, and program teams with clearly defined decision-making
and management charters
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Defining team member roles and responsibilities and selecting the
required team members consistent with these defined roles
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Designing team and cross-team processes that ensure efficient use of
MVI resources
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Developing a comprehensive implementation plan to ensure a successful
rollout, drive the completion of key design activities, and ensure
ongoing system monitoring and refinement
MVI expects its portfolio management system to deliver many benefits, including:
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R&D management driven by a portfolio, rather than an individual project,
perspective
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Managing all vaccine projects in a consistent and rigorous manner
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Making more consistent and transparent vaccine investment and development decisions
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Placing decision-making responsibility at the appropriate levels
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Facilitating more effective and credible reviews with external stakeholders,
including donors, scientific advisors, and R&D partners
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Enhancing the return on MVI R&D investments
MVI is now leading the way in the global health sector by leveraging
industry best practices to build and manage its R&D portfolio.
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