Global Health Case Studies

R&D Portfolio Analysis & Investment Strategy

Public Private Partnerships have become increasingly important for accelerating medicines and vaccines to developing countries where important treatments and preventions are needed the most. The Malaria Vaccine Initiative (MVI) was founded in 1999 with a mission to accelerate the development of promising malaria vaccine candidates, and ensure their availability and accessibility in the developing world.

Applied Strategies worked extensively with MVI to develop a five-year Applied Strategies worked extensively with MVI to develop a five-year R&D Strategy to focus the R&D organization on the goals most supportive of its overall mission. The scope of work included characterizing the current portfolio in a transparent and consistent way, identifying potential outcomes for current projects and likely follow-on activities given each outcome scenario, developing long-term R&D portfolio investment goals and decision criteria to guide future portfolio investments, and defining MVI's planning case to support fundraising and resource management decision-making.

The five-year R&D Strategy and planning case also provided the foundation for MVI's Core Grant Renewal proposal and motivated MVI to initiate an effort to design and implement both internal and external portfolio management structures and processes to ensure effective stewardship of the R&D portfolio well into the future.

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